Job Summary
Our mission is to deliver the undeliverable.
We are a venture-backed disruptive Machine Learning/AI therapeutics company focused on revolutionizing drug delivery. The Scientist will work in a fast-paced start-up environment playing a crucial technical role in synthesizing polymer of a range of different types for applications in gene delivery. The candidate will work with senior leadership and partner projects gaining broad internal and external exposure.
Essential Functions and Duties
· Perform routine synthetic operations of controlled polymer synthesis (e.g., reversible addition-fragmentation chain transfer polymerization, atom transfer radical polymerization, ring-opening polymerization, etc.), post-polymerization functionalization (e.g., radical/nucleophilic thiol addition, amidation reactions, etc.), and materials characterization of purified macromolecules (e.g., size-exclusion chromatography, NMR + IR spectroscopy, GPC, GC-MS, etc.).
· Develop systematic libraries of multi-functional self-assemblies that tailor polymeric materials of various lengths, monomeric building blocks, microstructures, architectures, and responsivity with biologics into new therapeutic applications.
· Perform solution-state characterization of polymeric assemblies with microscopic imaging and light scattering tools, as well as standard biological encapsulation/release assays.
· Assist with streamlining data collection, management, and storage of large datasets into a sustainable, growing data architecture in an agile manner.
· Collaborate with team members in the Bio-assay and ML/AI groups to rapidly synthesize polymers based on feature specifications.
· Prepare project reports and give presentations to internal and external stakeholders.
· Generate, analyze, and record high quality data and work with fellow team members to transfer data to ML/AI group.
Qualifications
Education and Experience
Ph.D. in Polymer Chemistry or related discipline.
Knowledge, Skills, and Abilities
· Strong working knowledge in polymer synthesis and characterization techniques.
· Familiarity with synthesis of targeting moieties (e.g., small-molecules, peptides, antibodies, carbohydrates, etc.) and bioconjugation.
- Ability to adapt and contribute in a rapidly growing organization.
- Excellent written and verbal communication.
- Comfortable working in a fast-paced environment.
- Must be comfortable with external partner/stakeholder interactions.
Additional Preferred Experience (desired, but not essential):
· Experience in an industry setting.
· Experience with micelles, liposomes, and lipids.
· Experience in working with computational techniques for polymer design.
· Experience with laboratory automation.
Working Conditions
This is a 100% on site, at the bench laboratory role.