The QC Chemist will be a critical member of the laboratory team responsible for performing analytical testing to ensure the quality, safety, and compliance of sterile injectable IV bag products at a newly established greenfield pharmaceutical manufacturing facility. This role will support the development, validation, and execution of analytical methods, ensure timely release of raw materials, in-process samples, and finished products, and maintain strict adherence to cGMP, FDA, and global regulatory standards. The QC Chemist will play a key role in establishing laboratory operations during the startup phase and sustaining high standards of laboratory excellence throughout routine commercial production.
Key Responsibilities:
- Prepare SOPs, test procedures, and product/material specifications
- Perform analytical testing of raw materials, in-process samples, stability samples, and finished products using validated methods (e.g., HPLC, GC, UV-Vis, FTIR, TOC, etc.).
- Develop and validate new analytical methods as required to support product development, regulatory submissions, and process optimization.
- Ensure compliance with cGMP, FDA, USP, and other regulatory standards in all laboratory activities, documentation, and data integrity.
- Participate in reviewing laboratory documentation including test protocols, reports, COAs, and change control records.
- Maintain laboratory instruments, arrange for routine calibrations, troubleshooting, and coordinate with vendors for preventive maintenance and repairs.
- Support laboratory readiness for regulatory inspections, audits, and customer visits by maintaining audit-ready documentation and laboratory practices.
- Assist in the preparation and execution of laboratory investigations, CAPA implementation, and root cause analysis for any analytical deviations.
- Collaborate with cross-functional teams including Manufacturing, Quality Assurance, Validation, and Regulatory Affairs to ensure seamless batch release and product compliance.
- Participate in training programs to ensure technical competency and adherence to evolving regulatory requirements.
- Contribute to continuous improvement initiatives focused on laboratory efficiency, data integrity, and compliance robustness.
Qualifications / Experience:
- Bachelor’s or master’s degree in chemistry, Pharmaceutical Sciences, or related field.
- 3+ years of experience in pharmaceutical QC laboratory, preferably in sterile injectable manufacturing.
- Strong hands-on experience with analytical instrumentation (HPLC, GC, UV, FTIR, etc.) and GMP-compliant laboratory operations.
- Knowledge of FDA cGMP regulations, USP standards, ICH guidelines, and data integrity expectations.
- Experience supporting laboratory investigations and regulatory inspections.
Skills / Competencies:
- Strong analytical and problem-solving skills.
- High attention to detail and accuracy in laboratory work.
- Good understanding of data integrity and documentation practices.
- Ability to work both independently and as part of a team in a dynamic startup environment.
- Excellent organizational, time management, and communication skills.
- Ability to adapt to evolving processes and regulatory requirements in a greenfield manufacturing setting.