Senior/Staff Bioinformatics Scientist/Engineer

 

Position Overview:
Moonwalk Biosciences is recruiting a Senior or Staff Bioinformatics Scientist/Engineer to join our multidisciplinary R&D team. This individual will play a key role in advancing Moonwalk’s mission to develop first-in-class medicines through the discovery and functional characterization of novel therapeutic targets. As a core member of the computational biology group, you will help transform complex multi-modal datasets into actionable insights to guide target selection and therapeutic development.

 

Key Responsibilities:

  • Develop and maintain reproducible, scalable, and cloud-based pipelines for processing diverse NGS datasets (e.g., RNA-seq, ATAC-seq, DNA methylation, single-cell).
  • Perform rigorous data analysis to identify patterns, biomarkers, and candidate therapeutic targets from high-dimensional genomic and epigenomic datasets.
  • Collaborate with wet-lab biologists, data scientists, and machine learning experts to interpret results and refine experimental design.
  • Document methods, pipelines, and results clearly and reproducibly for both internal stakeholders and external communication.

 

Required Qualifications:

  • M.S. or Ph.D. in Computer Science, Bioinformatics, Computational Biology, or related field with 2+ years of relevant experience.
  • Proficiency in one or more programming languages: Python, R, C/C++, Go, Rust, or equivalent.
  • Experience developing pipelines and tools to process sequencing data.
  • Familiarity with cloud computing environments (AWS, GCP, or Azure) and workflow management systems (e.g., Nextflow, Snakemake, Cromwell/WDL).
  • Deep understanding of statistical analysis and data visualization methods for genomics datasets.
  • Excellent collaboration, communication, and problem-solving skills.
  • Ability to thrive in a fast-paced, early-stage biotech environment.
  • Track record of impactful contributions, including peer-reviewed publications or open-source tool development.

 

Preferred Skills and Experience:

  • Experience with epigenomics datasets (e.g., bisulfite sequencing, ATAC-seq, chromatin accessibility profiling).
  • Background in multi-omics integration or machine learning applications in genomics.
  • Familiarity with CI/CD practices and containerization (e.g., Docker) in pipeline deployment.

Salary Ranges:

  • Senior Scientist/Engineer ranges from $130,000 to $173,000
  • Staff Scientist/Engineer ranges from $150,000 to $200,000

 

About Us:

Moonwalk Biosciences is pioneering a new class of precision epigenetic medicines. Its novel platform technology provides a complete view of the epigenome in health and disease, with the most advanced AI prediction of epigenetic targets, and the broadest set of epigenetic engineering tools. Moonwalk was Co-founded by Alex Aravanis, M.D., Ph.D., former CTO of Illumina, world-renowned scientist Feng Zhang, Ph.D. of the Broad Institute of MIT and Harvard, and a distinguished set of industry leaders and company builders. It has raised $57 million led by Alpha Wave Ventures, and joined by other leading life sciences investors ARCH Venture Partners, Future Ventures, GV, Khosla Ventures and YK Bioventures.

 

Equal Opportunity Employer:

Moonwalk Biosciences provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. 

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.