Position Title: Lupus Nexus Data Manager
Location: Remote locations
Background
The Lupus Research Alliance (LRA) is the world’s leading non-governmental, non-profit funder of lupus research. Over the past 20 years, the LRA has invested over $200 million in lupus research in more than 500 research and clinical studies. More recently, the LRA established an affiliate organization, Lupus Therapeutics (LT), which is responsible for the coordination, conduct, and management of a North American-based clinical trial consortium, the Lupus Clinical Investigators Network (LuCIN).
This is an exciting professional opportunity to support an initiative of critical importance to the lupus community from the ground up. Be part of a team of LRA/LT staff, academic and industry experts, and individuals with lupus who envision and bring to life a unique infrastructure that builds and integrates a patient registry with a linked biorepository, and a data and analytics platform. This resource, referred to as the Lupus Nexus (LNx), will expedite scientific discovery and clinical development, will accelerate precision medicine in lupus, and will ultimately transform lupus care.
Position Summary
The Lupus Nexus Data Manager will be part of the Lupus Research Alliance’s Research Department and will contribute to the build and management of the Lupus Nexus. This role is primarily responsible for the quality, security, and maintenance of clinical and research data, maintaining data provenance throughout the lifecycle of the program. The role will ensure that sufficient data quality is maintained so that the data can be effectively utilized by the lupus patient and research communities.
Responsibilities
Develop and oversee operational processes to ensure the quality, security, and maintenance of clinical and research data, maintaining data provenance throughout the lifecycle of the program.
Contribute to the development of the Data Governance and Management Plan to ensure the quality of Lupus Nexus’ datasets, data records, and data elements.
Contribute to the selection, design, configuration, and validation of the data repository, exchange, and analytics platform (DREAM) components. Work with external vendors in planning for the electronic capture and recording of various clinical, research, and biospecimen-related data.
Develop data flow schematics and logistics to coordinate the acquisition and distribution of clinical and research data. Define clinical data elements and collection modules from the study protocol and supporting documents. Assist with the development and maintenance of the Lupus Nexus data dictionary, ensuring that all data objects are uniquely defined, relevant, and non-duplicative.
Work with external vendors to ensure the seamless flow of data across all platforms and the availability of highly curated data for the end users of LNx.
Oversee the resolution and documentation of data queries as per established change management practices.
Oversee the acquisition and distribution of biospecimen analyses data from multiple platforms.
Contribute to vendor selection, contract development, and workflow operationalization for biospecimen analyses.
Maintain close partnerships with key stakeholders and work with functional leads to troubleshoot and resolve issues within the data collection and biospecimen analysis pipeline.
Contribute to the development of policies and procedures to support the release of data to the scientific community. Manage the review process for data requests. Develop, maintain, and report associated KPIs.
Credentials
· BS degree or higher in computer science, information technology, statistics, or a related field
· 8+ years of experience in a clinical trial and/or research data management with extensive experience in building and maintaining artifacts related to research study databases (e.g. eCRFs, ePROs, eClinROs, eConsent)
· Experience with biorepositories and multi-omic/molecular data types is preferred
Skills & Competencies:
Demonstrated ability to think strategically when planning and managing responsibilities
Hands-on, self-directed, detail-oriented, organized, and conscientious
Must work independently and prioritize and manage multiple projects within tight timelines
Team player who can build excellent working relationships both internally and externally
Salary and Benefits
LRA's core values include working toward health equity for all. As a reflection of our commitment to these values, we cover 100% of the cost of our employee's health, dental, and vision insurance from day one! Other benefits include a generous mix of paid time off, a flexible work environment, technology and internet stipend, and more.
The Lupus Research Alliance, Inc. is an Equal Opportunity Employer, committed to equal opportunity for all regardless of race, ethnicity, color, ancestry, national origin, citizenship, religion, sex, sexual orientation, gender identity/orientation/preference, class, or socioeconomic status, marital status, age, ability, or Veteran status.
All offers of employment are contingent upon the successful completion of a criminal background check, in accordance with state and local laws.