Senior Director, Technical Accounting

ROLE: Senior Director, Technical Accounting

DEPARTMENT: Finance & Accounting

REPORTING TO: Senior Vice President Finance and Administration

LOCATION: A corporate office or remote from the Employee’s home office

SALARY BAND: Senior Director, Technical Accounting $225,000 to $260,000 with an annual bonus target of 25%.

Final compensation will be commensurate with the candidate’s experience, education, skills, and overall alignment with the role’s requirements.

EQUITY GRANT ELIGIBLE: Yes

POSITION SUMMARY:

Reporting to the Senior Vice President Finance and Administration, the Senior Director, Technical Accounting will play a critical role in driving Ambros Therapeutics, Inc.’s financial reporting excellence, accounting integrity, and operational scalability as the Company advances its clinical pipeline and corporate growth initiatives.

This individual will be responsible for leading the Company’s technical accounting strategy, including complex accounting transactions, financial reporting policies, and audit readiness. The role requires strong technical expertise in U.S. GAAP, exceptional communication and organizational skills, professionalism, sound judgment, and adherence to regulatory and ethical standards governing financial reporting and internal controls.

ESSENTIAL DUTIES AND RESPONSIBILITIES

Lead and prepare all technical accounting matters, including interpretation and implementation of U.S. GAAP and emerging accounting standards.

Serve as a subject matter expert for accounting implications of financing transactions, valuation matters, and potential capital markets activities

Drive accounting assessments and documentation for complex arrangements, including clinical and contract manufacturing contracts, licensing and collaboration agreements, equity transactions, leases and business combinations.

Build and operationalize the Finance department's public-company reporting infrastructure to ensure the organization is fully prepared to meet SEC filing obligations as a public company

Responsible for SEC reporting to ensure the timely and accurate preparation of external financial reporting, including the drafting and finalization of Forms 10‐Q, 10‐K, S-1 and other SEC filings as required in compliance with SEC regulations and US GAAP disclosure requirements

Coordinate drafting and reviewing of SEC documents with internal and external parties (Executive Leadership Team, IR, auditors and outside legal counsel)

Work with Accounting department to ensure the timely and accurate preparation of monthly, quarterly, and annual financial statements (and related footnote disclosures) in accordance with US GAAP

Provide leadership in audit readiness, including coordination with external auditors and preparation of supporting documentation.

Assist with the administration of the equity compensation plan, including the accounting for RSUs/RSAs, Options and employee stock purchase plan under ASC 718.

Work closely with business leaders to prepare to scale end-to-end business processes, systems, and financial controls to support of the future growth of the Company into a commercial entity. This includes developing and executing Gross to Net (GTN) Revenue accounting process, systems and assumptions for GTN forecasts and budgets.

Oversee the design of internal control program and leads team to implement and perform the appropriate control functions to allow for a strong control environment. This also includes execution and testing of controls to ensure overall compliance with SOX 404 requirements and management certifications

Collaborate with cross-functional teams to establish and maintain scalable accounting policies, procedures, and internal controls appropriate for a growing biotechnology company.

Assist with Finance board meeting and audit committee materials

MINIMUM EXPERIENCE, EDUCATION, CERTIFICATIONS, & LICENSES:

Bachelor’s degree in Accounting, Finance, or related field required; Master’s degree preferred.

Active CPA license required.

Minimum of 8+ years of progressive accounting experience, including significant technical accounting responsibilities within publicly traded biotechnology, pharmaceutical, or life science companies.

Advanced understanding of GAAP, SEC Reporting, and financial analysis

Experience with disclosure management platform, Merrill Bridge, Workiva or RR Donnelley

Strong experience with complex accounting topics, including revenue recognition for collaboration arrangements, stock-based compensation, lease accounting, fair value measurements, and business combinations.

Proven track record of supporting external audits and building accounting infrastructure in high-growth environments.

Demonstrated integrity, accountability, and commitment to financial accuracy and compliance.

SKILLS & QUALIFICATIONS:

Problem solver with an entrepreneurial spirit, curious and innovative mindset, and ability to thrive in an agile environment.

Superior verbal, written, and presentation communication skills in English, with the ability to engage effectively across all levels of the Company and with external stakeholders.

Proven ability to develop and sustain relationships with auditors, advisors, consultants, and cross-functional business leaders.

Excellent leadership skills and demonstrated ability to manage cross-functional project teams of highly performing and motivated individuals.

Skilled in technical accounting research, financial reporting, policy development, and implementation of accounting standards.

Demonstrated ability to organize, prioritize and work effectively with minimal supervision in a constantly changing environment.

Must have knowledge of and be willing to comply with all regulatory/compliance policies and best practices consistent with the role and Company’s policies.

Ability to assess the inherent risks of a situation, their potential impact on a project and, based on this information, involve the appropriate team members to make timely decisions.

Ability to read and comprehend complex materials, including medical and scientific literature, policies, procedures, and instructions in English; write reports and memos; use logic and data to solve problems; assess needs and take appropriate actions; all with reasonable independence, business judgment, and professional discretion.

Upholds high ethical standards and maintains integrity in all activities.

Proficient with Microsoft Office Suite and related software.

WORK LOCATION AND TRAVEL REQUIREMENTS:

This position is based from an Ambros corporate office or remote from the Employee’s home office, subject to Company policy and business needs. If remote, a dedicated home office space that is professional in appearance, quiet, and secure where confidential conversations can occur and a high-quality high-speed internet connection are required.

Regardless of primary work location, the role requires in-person presence approximately once per month for multi-day meetings at the corporate headquarters or other designated locations, as determined by business or department priorities.

Occasional domestic travel is required, including overnight stays. Travel expectations may reach up to 10%, depending on operational priorities and Company needs.

PHYSICAL REQUIREMENTS & ENVIRONMENTAL CONDITIONS:

This position is primarily performed in a professional office or home-office setting.

With or without reasonable accommodation, the employee must be able to:

Operate a computer and standard office equipment;

Communicate effectively in person, via telephone, and through video conferencing platforms;

Travel independently, including overnight and international trips, and travel by personal vehicle and transit systems; and

Navigate office environments and other professional settings.

Additional requirements include:

Prolonged periods of sitting, standing, and walking;

Occasional lifting or carrying of items up to 20 pounds;

Ability to read, comprehend, and apply policies, procedures, and regulations written in English;

Ability to write clear, factual, and grammatically correct communications and reports in English; and

Ability to use logic and data for problem-solving and to exercise sound judgment.

EQUAL EMPLOYMENT OPPORTUNITY

As an equal opportunity employer, Ambros is committed to providing all applicants and employees with equal access to employment opportunities, regardless of sex, race, age, color, national origin, ancestry, disability, pregnancy, religion, genetic information, sexual orientation, transgender status, gender identity, marital status, military or veteran status, or any other characteristic protected by applicable law. All employees, officers, and representatives of Ambros are expressly prohibited from engaging in unlawful discrimination, harassment, or retaliation.

Consistent with all applicable requirements, Ambros will reasonably accommodate any qualified individual with a disability if such accommodation would allow the individual to perform the essential functions of the job, unless doing so would create an undue hardship on the Company.

Ambros also follows all applicable federal, state, and local laws governing work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and Immigration Reform and Control Act. Ambros is an E-Verify employer.

REASSIGNMENT OF DUTIES AND AT-WILL EMPLOYMENT

Nothing in this job description restricts Ambros’ right to assign or reassign duties, responsibilities, and work locations of this role at any time in its sole discretion. While this job description generally reflects Ambros’ current assessment of the essential functions for this role, it is not intended to be a complete list of the duties and responsibilities of this role, and it does not limit or restrict the duties and responsibilities that may be assigned from time to time.

Employment with Ambros is “at-will,” meaning that either the Company or the employee may terminate the employment relationship at any time, with or without cause or notice, reason, or justification, subject to applicable law.