ALX Oncology is a clinical-stage immuno-oncology company focused on helping patients fight cancer by developing therapies that block the CD47 checkpoint pathway. Our lead candidate, evorpacept, is a next-generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated proprietary Fc domain. For more information about us, please visit


The Head of Human Resources will report to the CFO, but will work closely with all of the senior leadership team. We seek a team member who wants to be fully integrated into every aspect of the company from research and development to business execution. The ideal candidate will have a flexible leadership style with the ability to operate at a highly strategic level, with a roll-up sleeves attitude and capability. The ideal candidate should have a strong background in the life science industry supporting companies in growth mode. The successful candidate will be required to reside within a commutable distance of our South San Francisco office. ALX Oncology Inc. follows a hybrid work model (i.e., part-time in South San Francisco office with flexibility to work part-time remotely).





  • Partnering with department heads and business functions to align the company’s current and future organizational structure with strategic corporate objectives.
  • Able to translate strategic business plans into HR strategic and operations plans.
  • Establish a physical presence, build relationships and trust with employees across functions and at all levels of the organization.
  • Establish the HR organization as a safe harbor for confidential HR matters and viewed as a respected leader on all HR related issues. 
  • Oversee benefits administration including compliance with appropriate state and federal legislation, obtaining competitive pricing, identifying new or alternative programs, and training staff on new benefits.
  • Manage external resources (recruiters, HR recruiting consultant, benefits providers) for cost-effective growth.
  • Ensure compliance with Human Resources-related laws and regulations including as a public company. Establish policies and procedures around core HR initiatives to ensure equitable and streamlined processes.
  • Develop and drive the overall talent acquisition strategy for the company, ensuring that the company hires best in class talent, who align with the ALX Oncology culture and values.
  • Oversee compensation (including Radford surveys), promotion and feedback practices to ensure equity (internally and vs. external benchmarks) to attract and retain the best talent.
  • Develop a comprehensive talent retention program inclusive of tangible (e.g. compensation, promotion) and intangible (e.g. training/coaching, scope realignment, resourcing) rewards.
  • Further develop and manage the performance evaluation process.
  • Manage onboarding experience to ensure colleagues are well-positioned for success in their new role.
  • Ensure a consistent focus on diversity and inclusion in all recruiting programs and processes and measure progress regularly.




  • Minimum of a bachelor’s degree or equivalent in Human Resources, Business, Organizational Development with a certification in HR management.
  • 10+ years of progressive leadership experience in Human Resources positions.
  • Experience in biotech and pharmaceutical environments preferred.
  • Demonstrated success in all Human Resources functional areas within a fast-paced, research and development focused environment.
  • Must be hands-on and capable of producing work with limited staff.
  • A proven track record of successfully managing employee relations issues, navigating, and leading the HR function through organization change.
  • The gravitas and experience to counsel and collaborate with executives and leaders in the company.
  • Demonstrated experience engaging with employees in a supportive manner; building strong internal relationships based on mutual respect and trust.
  • Ability to plan and oversee and execute HR operations processes.
  • Excellent interpersonal and coaching skills.
  • Highly responsible, self-motivated professional.
  • Strong leadership skills that include a desire for accountability.
  • Highly collaborative working style with the ability to influence others.
  • Superior work ethic that includes working autonomously with an appropriate sense of urgency and accuracy.
  • High energy, enthusiasm, and passion for the work.


Salary:  $225,000-$300,000


ALX Oncology is an equal opportunity employer. All applicants should be legally entitled to

work for any employer in the US. Title and salary are commensurate with experience. Our

compensation program includes competitive salary, equity participation and attractive bonus


This position has been filled. Would you like to see our other open positions?