Who We Are
Indapta Therapeutics is a clinical a clinical stage biotechnology company harnessing the natural power of the immune system to fight hematologic and solid cancers with its universal natural killer (NK) cell platform. The company’s allogeneic platform is based on a subset of NK cells, so called g-NK cells that are derived from healthy donors and are deficient in the FceR1g protein. These cells are particularly potent at killing cancer cells when combined with monoclonal antibodies currently clinically employed to specifically target and kill cancer cells. Indapta is working to bring this unique and powerful off-the-shelf cellular therapy to patients with cancer to overcome the limitations of currently available immunotherapies. The position is located at our Houston facility and is a full-time on site, laboratory position.
The Opportunity
We are seeking a highly qualified, motivated, and inspirational Senior Scientist in their Research Department to lead the development of novel NK cell therapeutics. The Senior Scientist will be responsible for the design and execution of high-quality lab research for data-driven pipeline expansion. The qualified candidate should possess an extensive knowledge of immunology with a proven track record of scientific excellence as demonstrated by a strong publication history and the ability to mentor the growth and development of lab staff with less experience. This position will report directly to the Director of Preclinical and Translational Research and may manage one employee (depending on candidate qualifications).
- Design and execution of high-quality lab research through their own work and in collaboration with other laboratory personnel.
- Design experiments for hypothesis-driven preclinical evaluation of NK cells to for novel therapeutic indications and mechanisms of action
- Analyze and present data to scientific leadership
- Rigorous documentation and organization
- Prepare written technical reports
- Mentoring/supervising research associate(s)
- Effectively collaborate within Research and relevant cross-functional areas.
Required Qualifications
- PhD with a minimum of four years post-graduate experience
- Significant knowledge of immunology, effector cell subsets, and cell therapies as evidenced by publication and/or presentation record.
- Expertise in flow cytometry, including the ability to design novel multi-color panels for use in preclinical development
- Highly proficient in the culturing and manipulation of primary immune and cancer cells
- Excellent practical knowledge of cell-based assays including cytotoxicity, cell proliferation, cytokine secretion.
- Hands-on experience gene-modification and gene-editing technologies (e.g., lentivirus, CRISPR, etc.)
- Excellent communication skills (written and oral)
- Strong work ethic and willingness to meet new challenges head on
- Prior experience managing lab personnel (e.g., research associates)
Preferred Qualifications:
- Previous experience in biotech/pharma R&D is preferred
- Working knowledge of and/or prior lab experience studying autoimmune diseases
- Experience with monoclonal antibody engineering and development
- Prior experience with IND-enabling studies
- Previous experience with incucyte or similar real-time live cell analysis
Indapta offers a highly competitive compensation package including company paid health care for each employee, stock options, 3 weeks of personal time off and an annual bonus program.