About Us
Indapta is a clinical a clinical stage biotechnology company harnessing the natural power of the immune system to fight hematologic and solid cancers with its universal natural killer (NK) cell platform. The company’s allogeneic platform is based on a subset of NK cells, so called g-NK cells that are derived from healthy donors and are deficient in the FceR1g protein. These cells are particularly potent at killing cancer cells when combined with monoclonal antibodies currently clinically employed to specifically target and kill cancer cells. Indapta is working to bring this unique and powerful off-the-shelf cellular therapy to patients with cancer to overcome the limitations of currently available immunotherapies. The research laboratory for Indapta is based in Houston, TX.
Indapta is seeking a self-motivated, driven and curious Post-Doctoral Fellow in their Research Department to develop and drive projects on the development of novel NK cell therapeutics and underlying molecular mechanisms. The Postdoctoral Fellow will be responsible for the design and execution of high-quality, cutting-edge research to expand our understanding of novel NK biology and biomarker-driven pipeline expansion. The qualified candidate has a PhD with an extensive knowledge of immunology and oncology with a proven track record of scientific excellence as demonstrated by a strong publication history. This position will report directly to the Director of Preclinical and Translational Research.
Responsibilities
- Design and execution of high-quality lab research through their own work and in collaboration with other laboratory personnel.
- Design experiments for hypothesis-driven preclinical evaluation of NK cells for novel therapeutic indications and mechanisms of action.
- Analyze and present data to scientific leadership.
- Rigorous documentation and organization
- Prepare written technical reports and manuscripts.
- Mentoring research associates
- Effectively collaborate within Research and relevant cross-functional areas within the company.
Qualifications
- PhD with a proven track record of excellence in Immunology or closely related field.
- Significant knowledge of foundational science and laboratory techniques in immunology, effector cell subsets, and cell therapies as evidenced by first-author publication(s).
- Excellent communication skills (written and oral).
- Strong work ethic and willingness to meet new challenges head on.
Required Technical Expertise
- Expertise in flow cytometry, including the ability to design novel multi-color panels for use in preclinical development
- Highly proficient in the culturing and manipulation of primary immune and cancer cells
- Excellent practical knowledge of cell-based assays including cytotoxicity, cell proliferation, cytokine secretion.
- Hands-on experience gene-modification and gene-editing technologies (e.g., lentivirus, CRISPR, etc.)
Additional Relevant Experience
- Working knowledge of and/or prior lab experience studying autoimmune diseases
- Experience with monoclonal antibody engineering and development
- Previous experience with incucyte or similar real-time live cell analysis
Indapta offers a highly competitive compensation package including company paid health care for each employee, stock options, 3 weeks of personal time off and an annual bonus program.