SUMMARY OF POSITION: Electra Therapeutics, based in South San Francisco, California, is a clinical stage biotechnology company developing therapies that target signal regulatory proteins (SIRP) for the treatment of immunological diseases and cancer.
The Director of Clinical Science will report to the Senior Director of Clinical Development and play a critical role in supporting clinical programs, with a strong emphasis on clinical data review, data analysis, and interpretation to ensure the quality, accuracy, and integrity of the studies. The ideal candidate will bring hands-on experience in clinical science with familiarity in data management process to partner effectively with cross-functional teams as well as a background in leading and conducting natural history studies. This role requires someone who is highly detail-oriented and thrives on diving deep into complex datasets, bringing both rigor and curiosity to uncover insights that drive program success.
KEY RESPONSIBILITIES:
- Provide scientific leadership for clinical programs including study, data interpretation, and reporting.
- Lead and participate in clinical data review and analysis to support data cleaning, patient safety review, and data integrity throughout the study lifecycle.
- Partner with clinical development, clinical operations, and data management to ensure high-quality data delivery.
- Contribute to data interpretation that informs clinical trial results, regulatory submissions, and publications.
- Support preparation of manuscripts, abstracts, posters, and presentations by assembling data outputs and ensuring scientific accuracy.
- Provide scientific and clinical input into study design, endpoint selection, and statistical analysis planning.
- Participate in cross-functional team meetings and act as a clinical science point of contact for internal and external stakeholders.
- Contribute to the development and review of key study documents (e.g., protocols, CRFs, data review plans, study reports, regulatory submissions).
- Support data management activities including database design input, eCRF development, and oversight of data flow.
QUALIFICATIONS:
- Advanced degree in life sciences (PhD, PharmD, M.S., or equivalent preferred).
- 7+ years of experience in clinical science and/or epidemiology within the biotech or pharmaceutical industry
- Demonstrated expertise in data review, analysis, and interpretation.
- Strong understanding of clinical trial methodology, Good Clinical Practice (GCP), and regulatory requirements.
- Familiarity with data management concepts, tools, and processes (e.g., EDC, eCRF design, query management), specifically in Medidata RAVE.
- Experience with natural history studies, epidemiology studies, and real-world evidence (RWE), in oncology and/or rare diseases
- Excellent organizational skills with the ability to manage multiple priorities in a fast-paced environment.
- Strong written and verbal communication skills, with proven ability to collaborate across functions.