Who We Are

Kinnate Biopharma Inc. is a clinical-stage precision oncology company focused on expanding on the promise of targeted therapies for those battling cancer.

The company is developing medicines for known oncogenic drivers where there are no approved targeted drugs and to overcome the limitations of marketed cancer therapies, such as non-responsiveness or acquired and intrinsic resistance.

Kinnate has two lead clinical programs being studied in solid tumors with RAF, NRAS and FGFR-driven alterations, and is rapidly progressing a pipeline of additional small molecule drug candidates as part of the Kinnate Discovery Engine.

The company is driven by the urgency and knowledge that patients are waiting for new, effective cancer medicines.   Come join us to help improve lives.

For more information, visit www.kinnate.com and follow us on LinkedIn.

 

Your Impact at Kinnate

We are seeking a Senior Scientist or Principal Investigator of Bioinformatics (Scientist) to join our Translational Research and Medicine team within Kinnate’s Clinical Development group. This is a position to support expansion of the company’s operations. Reporting to the Senior Director of Translational Medicine and Bioinformatics, the Scientist will be responsible for analysis and reporting of clinical genomics data. The Bioinformatics Scientist will work closely with the Translational Medicine and Clinical Development teams to discover, validate, and implement predictive genomic biomarkers. This position may be based in either San Francisco or San Diego with two-days a week office presence required. 

 

Responsibilities

·        Analysis of clinical biomarker data to better understand disease and target biology and to determine mechanisms of drug action, response and resistance

·        Develop/oversee clinico-genomic data analysis plans and manage relationships with clinical assay labs, genomic data vendors and academic research institutes 

·        Conduct multi-omic data analysis (RNA-seq, DNA-seq, cell-free, single-cell, proteomic, etc.) and integrate with other preclinical, clinical and real-world data sets

·        Build, improve and maintain databases and custom applications (eg. R Shiny apps) to maximize data accessibility and visibility by key stakeholders and project teams.

·        Keep well annotated analytical notebooks and code with appropriate version control

 

The Right Stuff

·        Familiarity with industry standards and regulatory guidance for analysis and reporting of clinical biomarker data is desired

·        Demonstrated ability in analysis of sequencing data and understanding of library prep/sequencing methods including RNAseq, DNAseq, ctDNA, single cell seq, etc.

·        Experience using public data/annotations such as AACR GENIE, ClinVar, Exome Variant Server, 1000 Genomes, OncoKB, TCGA and COSMIC

·        Graduate Degree (Ph.D./M.S.,) in a work-related field/discipline from an accredited college or university

·        Ph.D. plus 2 years or M.S. plus 6 years of experience analyzing clinical genomics and biomarker data for the Principal Investigator level.

·        Ability to build strong relationships with co-workers of various backgrounds and expertise

·        Ability to function at a high level in a team setting whether leading the group or acting as an individual contributor

·        Engaged in the mission of Kinnate Biopharma, able to act with flexibility and always with integrity

·        Strong communication skills and analytical abilities; follows best practices for reproducible research and code version control

·        Proficient in one or more of the following: R, tidyverse, Shiny, Python, bash

·        Familiarity with bioinformatics resources and tools such as IGV, BLAST, BWA, GATK, NCBI, EBI, GO, KEGG, etc.

·        Competent in biostats, statistical programming and data science

 

 

NOTE: This position summary is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

We offer a competitive total rewards package that provide our employees with the resources to pursue their goals, both at work and in their personal lives.  The salary reasonably expected to be paid for this role is $154,000 - $170,000.  The actual compensation and seniority level for this position will be determined based on relevant experience and qualifications.  This position is eligible for an annual cash bonus and equity awards.  Our employees are also eligible to receive other benefits including: 

 

·        Unlimited Paid Time Off

·        11 Company Paid Holidays - plus 2 annual paid “Refresher Days”

·        Wide variety of comprehensive health, dental, and vision packages – most with minimal to no out-of-pocket expenses for employees

·        Company contribution to 401k plan

·        Employee stock purchase program

·        Annual Massage Days

·        Free local gym memberships

·        Healthy Lifestyle Reimbursement Program

·        Home Office Reimbursement Program

 

Kinnate is proud to be responsible members of our communities. Subject to applicable law, we require all our employees to be fully vaccinated and boosted against the COVID-19 virus. Therefore, all applicants seeking a role located in the U.S. must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. 

 

EEO & Employment Eligibility.  Kinnate Biopharma Inc. is committed to building a diverse, equitable, and inclusive company. We provide equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Kinnate Biopharma Inc. also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of applicable law.