Who We Are
Kinnate is a rapidly growing, clinical stage precision oncology company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate’s mission is to expand the reach of targeted therapeutics by developing products for underserved populations. With our lead program currently conducting a Phase 1 clinical trial and another program expected to initiate a Phase 1 clinical trial in the first half of 2022 (subject to FDA clearance), it is a very exciting time to join Kinnate! In addition to the promising developments in our pipeline, Kinnate is financially strong with approximately $324.9 million of cash, cash equivalents and investments as of December 31, 2021, which is expected to fund current operations, including initiation of multiple registrational studies, into the second half of 2023. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors.
Kinnate is an employee-focused company providing a best-in-class benefits package which includes: cash salaries and bonuses and equity awards for all employees; employee stock purchase program; unlimited paid time off; annual paid “refresher” days for all employees; annual massage days for all employees; highly subsidized health benefits packages with a wide variety of provider options and minimal to no out of pocket expenses for employees; monthly stipend for employees who elect no health coverage through Kinnate; life and accidental death and disability insurance; company contribution to 401k plan; flexible office and remote work options; free local gym memberships; healthy lifestyle reimbursement program; home office reimbursement program; and commuter and walking/biking benefits. For more information, please visit www.kinnate.com.
Your Impact at Kinnate
We are seeking a highly motivated, innovative and collaborative PhD (or equivalent) level Oncology Biologist to lead and drive small molecule drug discovery efforts in a variety of oncology indications. The successful candidate will become an integral member of an oncology bioscience team focused on the discovery and delivery of novel anti-cancer therapies from early discovery through clinical development. As a key member of the oncology bioscience leadership team, in addition to delivering on the oncology pipeline, they will have the opportunity to deliver impact in additional areas including novel strategic initiatives and capability builds.
Key Responsibilities:
Lead biology delivery (cell and in vivo pharmacology) for small molecule oncology drug discovery programs from target selection into early clinical development
Identify biomarkers for target and pathway engagement, understand target engagement requirements for response, potential patient selection hypotheses and combination opportunities in disease relevant
models
Accountable for the characterization of all aspects of human pharmacology, including PK & metabolism, PKPD/exposure-response relationship assessment, clinical bioanalysis
In addition to collaborating with members of QPDS, the leader of Clinical Pharmacology also works in close collaboration with the leaders in Biology Drug Discovery, Translational Medicine, Clinical Research and Biostatistics to impact experiment/study design and facilitate line of sight from Discovery to Development in areas such as translational PKPD, bioanalytical chemistry, and model-informed drug development.
Partner with internal staff and external partners, oversee strategic planning and execution of clinical pharmacology and pharmacometrics activities
Adapt to changing project priorities and manage multiple projects
Direct line manager of lab and non-lab based scientists and mentor to junior scientists
The Right Stuff
PhD or equivalent or Masters with relevant experience in Cancer Biology or closely related area with a minimum of 10 years in biotech and/or pharma in early small molecule drug discovery
Demonstrated leadership of the biology and team at various stages of the drug discovery process
Strong track record of driving and leading projects from inception to clinical development
In depth knowledge of cancer cell and in vivo biology, along with techniques used to evaluate mechanisms of action of compounds
Ability to analyze, interpret and present biology data for a project enabling decision making
Experience in directly managing scientists and mentoring early career scientists
Strong interpersonal and communication skills and ability to work effectively across disciplines
NOTE: This position summary is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.
Kinnate is a science-driven company and we are proud to be responsible members of our communities. Subject to applicable law, we require all of our employees to be fully vaccinated and boosted against the COVID19 virus.
EEO & Employment Eligibility
Kinnate Biopharma Inc. is committed to building a diverse, equitable, and inclusive company. We provide equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Kinnate Biopharma Inc. also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of applicable law.
Recruitment & Staffing Agencies: Kinnate Biopharma Inc. does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Kinnate or its employees is strictly prohibited unless contacted directly by Kinnate’s internal HR Team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Kinnate, and Kinnate will not owe any referral or other fees with respect thereto.