It’s an exciting time to join us!
The Andelyn Biosciences’ Viral Vector Core group is seeking a motivated individual to join our growing team as a Scientist II.
The Scientist II role will learn and execute all aspects of the adeno associated viral (AAV) vector manufacturing in both adherent and suspension platforms. This includes leading the cell culture activities needed to meet the production schedule are planned, leading the preparation and inventory maintenance of solutions prepared in-house, and leading the daily workloads for the production and purification of AAV vectors. Scientist II will be responsible for adhering to VVC policies, protocols, and SOPs and following appropriate documentation procedures for preclinical AAV manufacturing. They will be responsible for troubleshooting issues and for presenting solutions to remedy problems. They will work with Management and Senior Staff to plan and execute operations to meet the objectives of Andelyn Biosciences and the VVC.
Schedule: Full-time (Benefits Eligible)
Location: Andelyn Development Center
5185 Blazer Pkwy
Dublin, OH 43017
Under the guidance and direction of the Associate Director of Viral Vector Core, essential functions of the Scientist II - VVC:
- Respond to, and take action from, alarm notifications from the applicable monitoring system(s) for laboratory temperature-controlled storage units that occur at any point during the assigned period of responsibility
- Leads the cell culture activities needed to meet the production schedule are planned, leading the preparation and inventory maintenance of materials and solutions prepared in-house
- Lead and schedule the daily workloads for the production and purification of AAV vectors
- Adhere to VVC policies, protocols, and SOPs and follow appropriate documentation procedures for preclinical AAV manufacturing
- Responsible for troubleshooting issues and for presenting solutions to remedy problems. They will work with Management and Senior Staff to plan and execute operations to meet the objectives of Andelyn Biosciences and the VVC
- Leads processes for research-grade and toxicology grade production at all scales following SOPs and protocols
- Responsible for assisting and leading operations in the support of viral vector production used to support preclinical studies
- Uphold a clean and safe work environment
- Provide training to staff
- Manage material inventory tracking in lab and SAP
- Anticipate, solve, correct, and prevent problems
- Draft, revise and follow SOPs and other process documents
- Work under the general supervision of senior staff and leadership
- Encourage a supportive team culture using our guiding principles and core values
- Exercise discretion, judgment, and personal responsibility
- Demonstrate a high level of integrity
- Maintain a positive attitude
- Operate within the Quality Management System applicable to the manufacture of phase appropriate material in the CMF
- Maintain compliance with applicable regulatory requirements for cellular and gene therapy products
- Attention to detail in all job functions with a strong focus on safety
- Performs in accordance with established policies, procedures, and techniques and requires training common experience or working knowledge related to the tasks performed
- Identifies problems and proposes solutions. Performs tasks as assigned by leadership
- Ability to work with independence based on applicable experience
- Works in a diverse and collaborative team environment utilizing clear communication to deliver high productivity and contributes to the success of team and goals
- Make decisions based on established procedures
- Nominal fiscal responsibility
- May require some travel
- Occasional involvement in customer relations
- Other duties as assigned
Knowledge, Skills and Abilities required
- Must possess relevant four-year degree OR relevant master’s degree OR relevant Ph.D., background in the life sciences, biotechnology, or gene therapy industries preferred
- Three years relevant (w/4 YR deg) OR no experience with (w/Masters or
- Experience in highly regulated field preferred
- Excellent communication, organization, and project management skills with the ability to manage multiple projects efficiently and adjust as priorities change
- Must be skilled in Microsoft Office (PowerPoint, Excel, Word) including data interpretation and reporting
- Ability to work independently as well as collaboratively in a diverse and inclusive work environment
- Must possess a client-focused mindset in daily tasks
- Must possess prior experience handling confidential information and the ability to maintain confidentiality
Minimum Physical Requirements
- Frequently Sitting
- Frequently Walking/Standing/Stooping
- Occasionally Independently lifting up to 50 pounds
- Frequently Talking on the phone or in-person
- Frequently Typing on a computer keyboard
- Frequently wear PPE on a regular basis
The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision.
Andelyn Biosciences is committed to a diverse and inclusive workplace. Andelyn is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or another legally protected status.
Andelyn Biosciences is currently operating under Executive Order 14042 that requires that employees of federal contractors and its affiliates be vaccinated against COVID-19, with some limited exemptions under the law. As Andelyn is both an affiliate and will be a federal contractor, proof of vaccination status will be required prior to first date of employment. Religious and medical exemptions may be considered depending upon the specific job duties and in accordance with applicable federal guidelines.