Overview of Andelyn Biosciences

Andelyn Biosciences is a biopharmaceutical Contract Development and Manufacturing Organization (CDMO) focused on advancing novel gene therapies from concept to commercialization. Located in the heart of Columbus, OH, the company has expanded to three buildings with more than 250,000 combined square feet of space.  The Andelyn Corporate Center (ACC) is dedicated to cGMP manufacturing, the Andelyn Development Center (ADC) for preclinical non-cGMP activities, and the Andelyn Plasmid Center (APC) for research and cGMP plasmid production.

Our Values are founded in our origin story.

The name “Andelyn” is a hybrid of two gene therapy patients who participated in pivotal Phase I clinical trials at Nationwide Children’s Hospital. Andrew received the first U.S. investigational gene therapy for Duchenne muscular dystrophy in 2006. Evelyn received experimental gene therapy for spinal muscular atrophy in 2015. “Andelyn” combines their names to represent all the families who have courageously participated in the research that makes today’s gene therapies possible. 

 

Through this journey, we have been able to accelerate the development and manufacturing of innovative therapies to bring more treatments to more patients. We are Pioneering Solutions that Turn Hope into Reality™ through our ACCTSions.

 

ACCOUNTABLE in our actions.

CURIOUS to discover.

COMPASSIONATE in our thinking.         

TRUSTWORTHY in our communications.

SUPPORTIVE of one another.

 

Employees are expected to perform the following essential functions under the framework of our ACCTSions.

 

What you will do.

Scientist I is responsible for supporting the gene therapy team by overseeing both the mammalian cell culture, prepared solution preparation, AAV vector production, and purification. This includes ensuring the cell culture activities needed to meet the production schedule are planned, assisting in the preparation and inventory maintenance of solutions prepared in-house, and organizing the daily workloads for the production and purification of AAV vectors. The Scientist I will be responsible for adhering to VVC policies, protocols, and SOPs and following appropriate documentation procedures for preclinical AAV manufacturing.   The Scientist I will work with other VVC staff to expand their knowledge base and skill set.  Additionally, the Scientist I will learn to troubleshoot issues as well as trend errors and work with management to identify areas for process improvement

  • Respond to, and take action from, alarm notifications from the applicable monitoring system(s) for laboratory temperature-controlled storage units that occur at any point during the assigned period of responsibility
  • Ensure the lab activities needed to meet the production schedule are planned, assisting in the preparation and inventory maintenance of materials and solutions prepared in-house and organizing the daily workloads for the production and purification of AAV vectors
  • Adhere to VVC policies, protocols, and SOPs and follow appropriate documentation procedures for preclinical AAV manufacturing  
  • Work with other VVC staff to expand knowledge base and skillset 
  • Learn to troubleshoot issues as well as trend errors and work with management to identify areas for process improvement 
  • Perform all processes for research grade and toxicology grade production scales following SOPs and protocols
  • Assist with Material Inventory in the lab and through SAP (ie. input ITRs, goods issue materials)
  • Exercise discretion, judgment, and personal responsibility
  • Demonstrate a high level of integrity
  • Maintain a positive attitude
  • Operate within the Quality Management System applicable to the manufacture of phase-appropriate material in the VVC
  • Maintain compliance with applicable regulatory requirements for cellular and gene therapy products
  • Attention to detail in all job functions with a strong focus on safety
  • Identifies problems and performs tasks as assigned
  • Work under the general supervision of senior staff and leadership
  • Works in a diverse and collaborative team environment utilizing clear communication to deliver high productivity and contributes to the success of the team and goals.
  • Documentation of all activities performed according to SOPs
  • Make decisions based on established procedures
  • Nominal fiscal responsibility
  • Limited involvement in customer relations
  • Other duties as assigned

 

 

What you bring to the team.

  • Must possess a relevant four-year degree, a background in the life sciences, biotechnology, or gene therapy industries preferred
  • No minimum experience
  • Experience in highly regulated fields preferred
  • Excellent communication, organization, and project management skills with the ability to manage multiple projects efficiently and adjust as priorities change
  • Must be literate in Microsoft Office (PowerPoint, Excel, Word)
  • Ability to work independently as well as collaboratively in a diverse and inclusive work environment.
  • Must possess a client-focused mindset in daily tasks
  • Must possess prior experience handling confidential information and the ability to maintain confidentiality

 

What you can expect when working at Andelyn.

  • The pride of contributing to the development and manufacturing of life-saving therapies.
  • The invaluable experience of being a part of building the foundation of a new organization.
  • The opportunity to work alongside experts who have over 10 years in the gene therapy field.
  • Competitive compensation
  • Eligible on day one for medical, dental, and vision insurance plans with basic vision at 100% company-paid
  • 160 hours of Paid Time Off annually
  • 11 Company Paid Holidays plus 2 floating holidays annually.
  • Company Paid Life Insurance
  • 401(k) Match
  • Company Paid short and long-term disability.
  • 4 weeks of Paid Parental Leave for birth and adoption
  • Adoption Assistance
  • Tuition Reimbursement and Student Loan Repayment Assistance
  • Company Paid LinkedIn Learning access.
  • Employee Assistance Programs
  • Flexible work options (role specific)

 

Andelyn Biosciences embraces diversity and is an equal opportunity employer and does not discriminate based on race, religion, national origin, gender, gender identity, genetic information, sexual orientation, protected veteran status, disability, age, or another legally protected status. As an organization, we are committed to creating an environment where everyone ACCTS.

This position has been filled. Would you like to see our other open positions?