Scientist III Gene Therapy Research

AavantiBio, Inc. is seeking a highly motivated gene therapy research scientist with a strong background in molecular AAV Virology to join our growing science team. The successful candidate will support our discovery efforts, as well as preclinical and clinical AAV gene therapy programs.


Full-time position with the opportunity for annual bonuses and participation in the Equity Incentive Plan. Benefits include high-quality health insurance plans including both gold and platinum Blue Cross Blue Shield plans, for which AavantiBio pays a competitive 85% of the health insurance premiums for our employees and their families.  In addition to health insurance, we have put in place flexible spending accounts and other benefits for our employees, including dental, vision, short- and long-term disability, group life insurance, AFLAC, and more. To assist our employees with their retirement planning, AavantiBio offers a safe-harbor 401(k) plan with a generous 6% company match.  



  • Work in a research laboratory
  • Optimize and execute viral vector production protocols, including staying up to date with current knowledge while driving innovation
  • Generate novel cell lines for recombinant virus production
  • Plan, design, and execute complex gene therapy research experiments in the lab
  • Support internal and external scientific research collaborations to increase team capabilities and address strategic needs
  • Take initiative to identify and support emerging technical approaches and gene therapy platforms that may drive increased value for pipeline programs
  • Demonstrate initiative, teamwork, collaboration and technical expertise as an independent and team player
  • Maintain organized and detailed electronic records in the electronic lab notebook to support internal documentation needs and regulatory submissions
  • Ability to multitask and contribute to multiple research projects under demanding timelines
  • Work as part of a multi-site team
  • Support and participate in R&D and project management meetings.



  • Ph.D. with 5+ years in molecular biology, virology with 3 years of relevant industry laboratory experience, with a focus on gene therapy.
  • First-hand experience with non-enveloped and enveloped viruses
  • DNA Virology techniques: viral vector generation and characterization, viral growth, titration, assays
  • Cell line optimization and characterization
  • Proficiency in tissue culture and recombinant virus work
  • Independently and proactively able to design and execute experiments including interpreting and presenting data.
  • Excellent bench skills with attention to detail and high standards for data integrity and quality.
  • Adherence to rigorous standards of good lab practices, safety, and documentation.


The level of this position will be based on the final candidate's qualifications.  Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities that are required of an employee for this job. Duties, responsibilities, and activities may change at any time with or without notice.


AavantiBio is committed to nondiscrimination with respect to race, creed, color, religion, age, disability, sex, sexual orientation, gender identity and expression, marital status, national origin, political opinions or affiliations, genetic information, and veteran status in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training.

About the company

AavantiBio, Inc.

11-50 employees - Biotechnology

AavantiBio is a clinical-stage biopharmaceutical company committed to developing and commercializing novel gene transfer and gene editing therapies for the treatment of rare and ultra-rare genetic diseases. The company is rapidly building a diverse portfolio of gene transfer and gene editing therapies to target debilitating genetic diseases for which the unmet medical need is high and for which there are typically no approved therapies treating the underlying disease.

AavantiBio is headquartered in Cambridge, MA with an additional location in Gainesville, FL. We are looking for exceptional individuals who share our passion for developing novel therapies to treat rare diseases and advancing the field of gene transfer therapy.

Developing genetic treatments for rare diseases is inspiring but challenging work and it takes dedication and courage which will make a meaningful impact on those who suffer from rare diseases. At AavantiBio, we will push each other to perform at our very best and build a company that not only our employees are proud of, but also the rare disease community, because everyone knows we are trying to make a difference in patients’ lives.

Come join our team!