Who we are

We are an integrated genetic medicines company developing targeted, disease-modifying medicines for patients with life-limiting respiratory diseases. Our treatments address the underlying genetic cause in underserved populations and have the potential to tremendously impact the quality and length of patients’ lives.

At ReCode, we bring a unique blend of rigor, creativity, and curiosity to our high-hurdle mission: harnessing our multi-platform approach to develop disease-modifying medicines. Our team is uniquely positioned to tackle this challenge, given our extensive experience in RNA delivery technologies, protein structure, tRNA biology, mRNA manufacturing, gene editing, and drug development.

Overview

The Scientist will design, plan and execute experiments focusing on In vivo pharmacology and toxicology. The Scientist will be responsible for designing studies to assess acute and chronic toxicological effects of IV and aerosol treatments in vivo, employing rodent models.


Responsibilities

  • Candidate will design studies to assess mechanism of action of molecules, acute and chronic toxicological effects of aerosol treatments in vivo, employing animal models (rodent and other)
  • Candidate is expected to be excellent in rodent handling skills and proficient at routine routes of administration (e.g. IV, SC, IP, IM, ID, topical, intra nasal) Candidate will carry out in vivo experiments on approved protocols that involve collecting and analyzing data
  • Experiments will relate to aerosol toxicology and delivery, intranasal dosing, bronchoalveolar lavage collection and in vivo imaging (IVIS imager)
  • The individual will be required to interact cross-functionally and across the enterprise, as well as manage multiple projects to ensure project timelines are met
  • Responsibilities also include writing IACUC protocols

Qualifications:

  • PhD in pharmacology, immunology or Biology or other related field. Postdoctoral training and industry experience preferred
  • Required 3-5 years experience with in vivo pharmacology/toxicology experience with rodent handling
  • Both mouse and rat handling strongly preferred
  • Hands-on experience with acute or chronic models of inhalation exposure in rodent and non-rodent systems preferred
  • Experience with bronchial/tracheal/ciliated cell systems is preferred
  • Direct experience with aerosol toxicology and delivery, intranasal dosing, bronchoalveolar lavage and in vivo imaging and modeling is preferable
  • Creativity and the ability to lead and/or work within an interdisciplinary team in order to achieve technical and corporate milestones
  • Comfortable working in a small team environment
  • Team player willing to pitch in where needed

ReCode Therapeutics (www.recodetx.com) offers a competitive compensation / benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development. ReCode Therapeutics is an Equal Opportunity Employer.

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