Artisan is building a revolutionary platform for editing mammalian cells for therapeutic applications. We are seeking talented candidates to work on cutting-edge interdisciplinary projects in the area of immune cell engineering. This person will join Artisan Development Labs in Louisville, Colorado and will act in coordination with the genome engineering group on development and deployment of mammalian genotyping assays.
Responsibilities and tasks:
The candidates will use experience in next generation sequencing technologies and targeted nucleic acid detection technologies to help develop and improve genotyping assays for the successful translation of immune cell engineering technology into the clinic. The position requires flexibility, creativity, and the ability to work effectively in a multi-disciplinary team. Candidates should have a capacity for creativity and innovation, as well as an ability to effectively communicate (written and verbal) to achieve company goals.
Specific responsibilities will include:
- Design and conduct experiments aimed at development and qualification of genotyping and NGS assays to support immune cell engineering
- Write technical reports and SOPs as well as presentation of technical data
- Train and disseminate techniques and procedures to other team members and partners
- Work with bioinformatics team to generate and analyze complex genomic datasets to draw meaningful conclusions
- Work with a cross functional team for the development of novel assays and techniques, and support the submission of patents and other intellectual property
- Deliver plans and results in clear and concise manner with cross-functional colleagues through oral updates, written reports and technical meetings.
- Troubleshoot, propose next steps or suggest alternate strategies within complex systems and assays.
Qualifications:
MS or PhD degree in a relevant discipline such as Cell or Molecular Biology, Biochemistry, or Chemical Engineering with at least 2-5+ years of relevant experience in industry
- Expertise in sequencing and molecular biology, with hands-on skills on DNA/RNA extraction, library construction, automation, and quality control is required
- Experience working with cross-disciplinary teams for SOP development, establishing controls for experimental quality (repeatability, reliability)
- Ability to review and implement methodologies described in scientific literature
- Experience interfacing with bioinformatics scientists to quality control and interpret sequencing data
- Attention to detail, ability to work in a team-oriented, multidisciplinary environment and able to work to timelines is a must
- Excellent independent problem solving and troubleshooting skills
Artisan offers a competitive base salary, benefits package and stock options to all team members. Come join Artisan, currently housed in the Fitzsimmons Innovation center and soon to be located in Louisville, CO.
Send inquiries and applications to careers@artisancells.com