Spirovant is a gene therapy leader focused on changing the course of cystic fibrosis and other respiratory diseases. Our gene therapy technologies are using adeno-associated virus (AAV) and lentivirus vectors designed to overcome the historical barriers that have prevented effective genetic treatments for conditions such as cystic fibrosis. We are a rapidly growing company located in the biotech heart of University City, Philadelphia.

To support our continued expansion and enable our future success, Spirovant is looking for a Research Associate.


  • Establish, maintain, and perform experiments on cells in culture, including cell lines and primary cells.
  • Conduct molecular and biological research to optimize AAV and lentivirus vectors to enhance the efficiency of airway cell targeting and transduction.
  • Evaluate expression and function of various transgene products using established methodologies.
  • Generate, manage, evaluate, and maintain critical data in a highly organized manner.
  • Maintain compliance with facility mandated chemical inventory and safety requirements.
  • Help prepare technical reports, papers, tech transfer documents, presentations and SOPs for regulatory or use in further research activities as needed.
  • Be a highly collaborative team member capable of working with other scientists in the Team as well as cross-functionally.


  • Bachelor’s degree in relevant biological sciences (i.e. molecular biology, biochemistry, pharmacology, or a related field).
  • Ideally, 2 years of experience in a laboratory or industry setting.     
  • Experience with cell culture techniques; experience with working with primary cells a plus.
  • Technical experience with molecular biology (PCR, ddPCR, nucleic acid extraction), biochemical analysis (western blot, ELISA, flow cytometry, FACS), cell transfection/infection and immuno-histological methods.
  • Experience with imaging techniques, such as fluorescent microscopy and analysis a plus.
  • Well organized, able to multitask and handle several projects simultaneously.
  • Proficient in Microsoft Excel, Graphpad Prism, and/or other analytical software.
  • Proficiency in using electronic laboratory notebooks (ELN).
  • Able to organize and prepare scientific data for internal and external presentations.
  • Excellent verbal and written communication skills.
  • The candidate will be a high-level individual contributor who is self-motivated and integrates effectively into the team, enhancing the team’s overall efficiency and productivity