Spirovant is a gene therapy leader focused on changing the course of cystic fibrosis and other respiratory diseases. Our gene therapy technologies are using adeno-associated virus (AAV) and lentivirus vectors designed to overcome the historical barriers that have prevented effective genetic treatments for conditions such as cystic fibrosis. We are a rapidly growing company located in the biotech heart of University City, Philadelphia.
To support our continued expansion and enable our future success, Spirovant is looking for a Research Associate.
Responsibilities:
- Establish, maintain, and perform experiments on cells in culture, including cell lines and primary cells.
- Conduct molecular and biological research to optimize AAV and lentivirus vectors to enhance the efficiency of airway cell targeting and transduction.
- Evaluate expression and function of various transgene products using established methodologies.
- Generate, manage, evaluate, and maintain critical data in a highly organized manner.
- Maintain compliance with facility mandated chemical inventory and safety requirements.
- Help prepare technical reports, papers, tech transfer documents, presentations and SOPs for regulatory or use in further research activities as needed.
- Be a highly collaborative team member capable of working with other scientists in the Team as well as cross-functionally.
Requirements:
- Bachelor’s degree in relevant biological sciences (i.e. molecular biology, biochemistry, pharmacology, or a related field).
- Ideally, 2 years of experience in a laboratory or industry setting.
- Experience with cell culture techniques; experience with working with primary cells a plus.
- Technical experience with molecular biology (PCR, ddPCR, nucleic acid extraction), biochemical analysis (western blot, ELISA, flow cytometry, FACS), cell transfection/infection and immuno-histological methods.
- Experience with imaging techniques, such as fluorescent microscopy and analysis a plus.
- Well organized, able to multitask and handle several projects simultaneously.
- Proficient in Microsoft Excel, Graphpad Prism, and/or other analytical software.
- Proficiency in using electronic laboratory notebooks (ELN).
- Able to organize and prepare scientific data for internal and external presentations.
- Excellent verbal and written communication skills.
- The candidate will be a high-level individual contributor who is self-motivated and integrates effectively into the team, enhancing the team’s overall efficiency and productivity