Associate Scientist / Scientist I  In Vitro Pharmacology

November 2024

Department:  Biology

 

Work Location:  Corporate Headquarters (South San Francisco)

 

Position Summary

TCG Labs-Soleil is seeking a motivated and intellectually curious Associate Scientist/Scientist I to join our biology team. The ideal candidate will bring a deep passion for drug discovery and a collaborative spirit to help drive forward our mission of efficiently translating scientific insights into therapeutic solutions for patients facing serious diseases. Leveraging knowledge and experience of various techniques in cell biology and molecular biology, this candidate will focus on in vitro assay development to support drug discovery efforts for our diverse pipeline projects.

Responsibilities

 

  • Design, develop, and optimize in vitro biochemical and cell-based assays utilizing a variety of techniques to assess potential drug candidate activities and elucidate mechanisms of action.
  • Collaborate with in vivo pharmacology scientist to support endpoint sample analysis or establish ex vivo cellular assays.
  • Analyze experimental data, interpret results, and generate actionable insights to help drive project decision-making.
  • Contribute to multiple projects simultaneously and work cross-functionally with colleagues in groups such as antibody discovery or protein science.
  • Keep meticulous records of experiments performed and maintain electronic lab notebook entries.
  • Provide regular progress updates and present data at internal team meetings.

Qualifications

  • M.S. in Cell Biology, Molecular Biology, Immunology or other relevant discipline with 6+ years of relevant experience, or B.S. with equivalent experience.
  • Strong cell culture skills including cell lines and primary cells.
  • Extensive experience in developing and optimizing cell-based assays using diverse platforms such as flow cytometry, ELISA, MSD, Luminex and qPCR.
  • Experience in molecular and cell biology techniques such as CRISPR, cell transfection, stable cell line generation.
  • Experience working on cellular models of diverse disease areas is desirable, including but not limited to immune-related diseases and oncology.
  • Proficiency in data analysis and interpretation with experience using relevant software and statistical tools.
  • Excellent communication and presentation skills.

Company Overview

TCG Labs-Soleil, established in partnership with The Column Group, a science-focused venture capital firm, is pioneering a novel ‘venture capital-biotech’ model. Our core mission is to efficiently translate scientific insights into therapeutic solutions for patients facing serious diseases. This model supports scientific entrepreneurs from the initial idea to clinical proof of concept (PoC) by combining a dedicated fund (TCG Labs) with our independent, evergreen R&D center led by a top-tier scientific team (Soleil). Together, we create an integrated ecosystem that fosters the development of single-asset portfolio companies, strategically poised for transacting after clinical PoC.

For more details, visit TCGLSoleil.com and follow us on LinkedIn

EEO Statement

TCG Labs-Soleil is an Equal Opportunity Employer. We do not discriminate against qualified applicants based upon any protected group status, including but not limited to race, religion, color, creed, sex (including breastfeeding and related conditions), gender identity/gender expression, pregnancy (including childbirth and related conditions), national origin, ancestry, age, marital status, military or veteran status, sexual orientation, genetic information, physical or mental disability or medical condition as defined by applicable equal opportunity laws. Any request for accommodation can be directed to contact@tcglsoleil.com. 

Benefits and Compensation 

TCG Labs-Soleil provides a competitive benefits package that includes access to Medical, Dental, and Vision Insurance, Life Insurance, Short and Long Term Disability, Health Savings Account (HSA), Flexible Spending Accounts (FSA), 401k plan and PTO.

The anticipated salary range for fully qualified candidates applying for this role will be $91,000 - $175,000 annually (not including discretionary bonus, equity, and benefits). The final salary offered will be dependent on several factors that include but are not limited to relevant previous experience including duration and type of experience within the industry, education, and internal equity.

Staffing Agencies

TCG Labs-Soleil does not accept unsolicited agency resumes and will not pay fees to any third-party agency or firm that doesn’t have a signed agreement with TCG Labs-Soleil. Please do not send agency CVs/resumes through TCG Labs-Soleil website or TCG Labs-Soleil Employees.  Inquiries must be sent to contact@tcglsoleil.com with the Subject Heading:  Staffing Agency Request.