Philadelphia, PA


Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching targeted, potentially curative, cellular therapies for patients with autoimmune diseases. The CABA™ platform includes two strategies to treat and potentially cure many of the most common and challenging autoimmune diseases. The CARTA strategy, or Chimeric Antigen Receptor T cells for Autoimmunity, is designed to potentially reset the immune system by causing transient B cell depletion with early academic clinical data suggesting the potential of this strategy to transform treatment in patients with SLE and the possibility of cures in rheumatoid arthritis, myositis, and systemic sclerosis, among others. Our lead product candidate using the CARTA strategy is CABA-201, 4-1BB-containing CD19-CAR T designed specifically to treat patients with autoimmune diseases with high unmet need, including systemic lupus erythematosus (SLE), myositis, systemic sclerosis, and generalized myasthenia gravis, and which uses a CD-19 binder that has an encouraging clinical tolerability profile. In addition to our CARTA candidate, CABA-201, we have a clinical-stage pipeline of Chimeric AutoAntibody Receptor T (CAART) cells targeted to the cells responsible for autoantibody-mediated autoimmune diseases.  Cabaletta Bio’s headquarters are located in Philadelphia, PA. For more information, visit and follow us on LinkedIn and X (Twitter).


Uniquely Differentiated. Rapid. Elegant. 

At Cabaletta, we are driven by the shared mission of developing cures, where a patients’ own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. #CabalettaCrew.  


We’re proud to be a Great Place to Work-Certified™ company! #GPTWcertified Check out what our employees say makes working here so great:  Working at Cabaletta Bio Inc | Great Place to Work® 



About the Position


Reporting to the Director IT and Data Sciences, we are seeking a Lab Information Management (LIMS) Administrator to be responsible for leading the implementation, development, customization, and continuous improvement of the Laboratory Information Management System to ensure it meets the specific needs of our laboratory operations.  The individual will work closely with Laboratory Operations, Computational Biology, and other stakeholders to enhance the efficiency and functionality of the LIMS system. This is a hands-on role that requires design/coding with deep LIMS development experience and integration/functional support of laboratory endpoints.

This role is located in Center City, Philadelphia. We are a hybrid work environment, and the expectation is that this role will be in the office 2+ days per week (as required), with the remainder of the week remote. 



  • Accountable for design, implementation, customization, and configuration of the LIMS software to align with laboratory workflows, data requirements, and reporting needs.
  • Design, develop and maintain custom modules, data entry UI, and scripts to automate tasks and integrate the LIMS with other laboratory instruments and systems.
  • Provide technical leadership and mentorship to CRO partners, LIMS team, laboratory staff, troubleshoot issues and address user inquiries related to LIMS functionality.
  • Ensure that the LIMS system complies with industry regulations, standards, and data security protocols.
  • Responsible for the administration of the LIMS supporting laboratory operations to include, but not limited to, systems analysis, customized reports, modifications, user account management, barcode/printer management, and upkeep of systems administration tasks.
  • Create and maintain comprehensive documentation for customizations, configurations, mapping workflows (such as: SOPs, User Guides, Training Materials, Test Plans, Validation Documents)
  • Assists staff and CRO partners in understanding and using technology; conducts regular staff technology presentations and trainings.
  • Manage SDLC of the LIMS system and Lab Workstations.
  • Collaborate with the QA/CSV department to support the validation process through implementation activities; develop and/or execute test scripts as required.
  • Drive and support data integrity processes for LIMS system and Lab Workstations.
  • Other assignments and projects as required.



  • Bachelor’s degree with 3+ years of working experience as a lead LIMS Developer or similar role in biotech, pharmaceutical, or life sciences industries.
  • Experience with IT projects supporting clinical drug development preferred.
  • Experience with Thermo Systems Sample Manager LIMS system is a plus.
  • Strong experience in software development using Python, Java, Bash, Perl, and SQL.
  • Experience in Windows and Linux endpoint operating systems.
  • Excellent project management communication, and problem-solving skills.
  • Strong collaboration and influence skills to work effectively with cross-functional teams.
  • Strong curiosity and the ability to learn quickly and adapt to a fast-changing environment.
  • Strong background in client support and demonstrated ability to work with clients who have a wide variance in IT and computing skill levels.
  • Strong team orientation and passion for continuous self-development
  • Comfortable in a fast-paced small company environment.
  • Experience in industry or in a startup industrial setting is preferred. 


Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression.


For more information, please visit


Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.


Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.


Cabaletta Bio, Inc. does not accept unsolicited resumes from recruiters, employment agencies, or staffing firms. To conduct business with Cabaletta, a Master Services Agreement (MSA) must be executed and confirmed prior to submitting any information relating to a potential candidate. Without a signed MSA, Cabaletta shall not be responsible to any individual or entity for any payment relating to any form of fee or compensation.


And, if a resume or candidate is submitted by a recruiter, an employment agency, or a staffing firm without a fully executed MSA, Cabaletta has the unrestricted right to pursue and hire any of those candidate(s) without any legal or financial responsibility to the recruiter, agency, and/or firm.