Senior Director, New Product Planning

Philadelphia, PA (Hybrid or HQ)

Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. Cabaletta Bio’s headquarters and labs are located in Philadelphia, PA. For more information, please visit www.cabalettabio.com and connect with us on LinkedIn.

 

Uniquely Differentiated. Rapid. Elegant.

At Cabaletta, we are driven by the shared mission of developing cures, where a patient’s own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. #CabalettaCrew. 

We’re proud to be a Great Place to Work-Certified™ company! #GPTWcertified Check out what our employees say makes working here so great:  Working at Cabaletta Bio Inc | Great Place to Work®

 

Position Description:               

 

This role can be based out of our Philadelphia, PA headquarters or hybrid. 

Reporting to the Chief Business Officer, the Senior Director, New Product Planning at Cabaletta Bio will serve as the product-strategy lead across the development lifecycle, generating and translating deep market understanding into actionable product decisions. This role is responsible for defining and maintaining target product profiles, generating market insights, partnering with commercial on customer understanding and bottom-up forecasting pre-launch while ensuring that development, regulatory, and commercial strategies are aligned to deliver differentiated, clinically meaningful therapies that meet unmet patient and provider needs.

 

Key Responsibilities:

  • Lead product-focused new product planning across early- and late-stage programs, including definition and evolution of Target Product Profiles (TPPs).
  • Design and oversee qualitative and quantitative market research to inform product design, indication prioritization, and differentiation strategy.
  • Translate customer, payer, and market insights into clear product requirements and strategic recommendations for development teams.
  • Partner closely with Clinical Development, Regulatory, and Medical Affairs to ensure development plans reflect real-world market needs and constraints.
  • Assess competitive landscapes, evolving standards of care, and emerging data to guide product positioning and lifecycle planning.
  • Develop product narratives that articulate clinical value, unmet need, and differentiation for internal decision-making and external stakeholders.
  • Support portfolio prioritization through product-level assessments, scenario analyses, and value framing.
  • Prepare and present product strategy updates to governance forums and senior leadership.
  • Establish best practices, tools, and frameworks for product planning and insight generation across the portfolio.

 

Qualifications:

  • Bachelor’s degree in life sciences, business, marketing, or a related field; advanced degree (MBA, PharmD, MS) preferred.
  • 10+ years of experience in product strategy, new product planning, marketing, or commercial insight roles within biopharmaceuticals.
  • Demonstrated expertise in market research methodologies, insight generation, and translating findings into product strategy.
  • Strong understanding of the drug development lifecycle and how product decisions influence clinical, regulatory, and commercial outcomes.
  • Excellent communication skills with the ability to synthesize complex information into clear, decision-oriented recommendations.
  • Proven ability to influence cross-functional teams without direct authority.
  • Strong team orientation and passion for continuous self-development
  • Experience supporting development-stage or pre-launch assets, including early asset strategy and indication expansion, highly preferred
  • Background in rare disease, autoimmune, cell therapy, or other specialty therapeutic areas, highly preferred
  • Hands-on experience working with external vendors for market research, advisory boards, and primary research, highly preferred
  • Comfort operating in a high-growth, science-driven biotechnology environment, highly preferred

 

Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression.

For more information, please visit  https://www.cabalettabio.com/join-our-crew

Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.

Cabaletta Bio, Inc. does not accept unsolicited resumes from recruiters, employment agencies, or staffing firms. To conduct business with Cabaletta, a Master Services Agreement (MSA) must be executed and confirmed prior to submitting any information relating to a potential candidate. Without a signed MSA, Cabaletta shall not be responsible to any individual or entity for any payment relating to any form of fee or compensation.

And, if a resume or candidate is submitted by a recruiter, an employment agency, or a staffing firm without a fully executed MSA, Cabaletta has the unrestricted right to pursue and hire any of those candidate(s) without any legal or financial responsibility to the recruiter, agency, and/or firm.

 

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