Turnstone Biologics is a clinical-stage, immuno-oncology company focused on the development of next-generation oncolytic viral immunotherapies for patients with a broad range of solid tumors. Turnstone’s unique, first-in-class oncolytic viral immunotherapies harness anti-tumor immunity by combining the potent tumor-killing effects of an oncolytic virus with a tumor-targeted T-cell vaccine. Our robust pipeline of early-stage biologics, based on our MG1 oncolytic virus platform, are in development for multiple solid tumors and are being evaluated in combination with other immunotherapies, including checkpoint inhibitors, to drive unprecedented, durable T-cell immune responses. Turnstone continues to build a world-class, high-performing company that embraces being a learning organization with a sense of urgency. Turnstone has a seasoned board of directors and venture capital partners, and highly active R&D efforts led by a world-class scientific management team. Turnstone is co-located in Ottawa, and Hamilton, Canada and New York, USA.
Position Overview:
Reporting to the Sr. Scientist in Ottawa, the position of Research Technician is responsible for supporting the testing of novel oncolytic vaccine constructs to contribute to Turnstone Biologics growing pre-clinical pipeline.
Our company’s technology is based around replicating oncolytic virus vaccines engineered to target tumours and launch massive tumour targeting immune responses. The core of this technology lies in the designing and building of these genetically constructed viruses. Your role will be to join a team of immunologists and molecular biologists who engineer and test these nanomedicines for preclinical and clinical development. There will be additional opportunities to work with our CMC team and other R&D members to continually refine the technology and manufacturing process for this class defining technology. If you have experience with manual, or robotic automation of, cell based and biochemical assays including ELISA, ELISpot assay, PCR and/or mammalian cell culture, are meticulous and driven to achieve; then this opportunity may be just what you are looking for.
The Research Technician will work along side senior researchers and project teams and participate in designing and executing cell-based immunology and virology assay following established laboratory standard operating procedures (SOPs). The incumbent is expected to prepare data/figures to report directly to senior research staff in support of multiple projects. Additional responsibilities will include inventory management; organize freezers; routine maintenance; calibration and troubleshooting on laboratory equipment. We have an open, transparent and dynamic culture that embraces scientific excellence, integrity, urgency, partnerships with key stakeholders and continuous learning/improvements.
Experience & Qualifications:
- MSc, BSc or community college diploma plus 2-3 years’ experience in an academic or industrial laboratory or combination of education and experience.
- Expert in mammalian cell-based and biochemical experimentation
- Must have good analytical and problem-solving abilities
- Robotic automation experience preferable
- Self-starter with a strong work ethic and attention to detail
- Knowledge and experience with standard software (e.g. LIMS, Microsoft Office Suite, Graphpad Prism)
- Knowledge and commitment of Occupational Health and Safety Procedures in a laboratory.
Turnstone Biologics welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process. We thank all applicants for their interest, however, only those selected will be invited for an interview.