Job Overview:        

 

The individual will be expected to support cross-functional development teams as well as conduct scientific research under supervision within a biological laboratory environment.

 

Responsibilities:

•        Develop deep gene sequence strategies such as NGS workflow to advance the characterization of DNA molecules in rAAV vector preparation.

•        Lead characterization studies for AAV gene therapy vectors. e.g., AAV genome, plasmid, and residual DNA characterization studies

•        Implement NGS data analysis pipeline using appropriate software and bioinformatic tools.

•        Work with vendor and other resources for long read sequence analysis (e.g., PacBio and Oxford Nanopore sequencing).

•        Qualify and validate analytical methods.

•        Author technical documents including Standard Operating Procedures (SOP), protocol, report, and technical reports.

•        Conduct a wide range of analyses (routine and non-routine) to support bio-pharmaceutical testing while maintaining documentation standards that meet GMP requirements.

•        Support regulatory filing as needed.

•        May supervise and train technical staff as need arises.

Requirements:

 

•        BS/MS in the scientific field of study with 8+ years of relevant experience working or shorter amount of working experience with a PhD and/or post-doc in the scientific field.

•        Must have a hand on experience of NGS technique using illumine system and data analysis.

•        Long read sequence experience preferred.