Who We Are

Programmable Medicine (a spin-out from Ashvattha Therapeutics) is an innovative, science-driven biotechnology company dedicated to developing a new class of drugs that identify and treat diseased cells with unprecedented precision. Our proprietary hydroxyl dendrimer (HD) platform, exclusively licensed from Johns Hopkins University, allows for the creation of hydroxyl dendrimer therapeutics (HDTs), which link known small molecule drugs to HDs for selective delivery with sustained effect in diseased tissues. We believe this approach to precision medicine has the potential to change the standard of care across a wide range of diseases. As pre-revenue organization, we are focused on advancing our pipeline through research, preclinical, and early clinical development while building a scalable operational foundation.

The Position

The successful candidate will play an integral role in ensuring the smooth and efficient operation of clinical trials by managing the supply chain of investigational medicinal products (IMPs).  You will collaborate with cross-functional teams to ensure study timelines and on time in full delivery of clinical supplies to investigational sites while maintaining compliance to Good Manufacturing Practice (GMP) and Good Clinical Practice (GCP) guidelines.  This position requires working on site a minimum of 3 days per week; preference will be given to candidates who are able to work on site 5 days per week.

Job Responsibilities

  1. Clinical Supply Chain Planning and Management:
    • Participate in strategic clinical trial material forecasting and planning. Establish appropriate resupply production staging and execution
    • Develop and implement clinical supply chain strategies aligned with study timelines and objectives.
    • Manage supply constraints, risks and changes.
    • Authorize, review and approve IP user instructions e.g. clinical labeling, study protocols, pharmacy manuals, study specific Clinical Supply Plan etc.
  1. Clinical Supply Chain Production and Procurement
    • Lead global sourcing strategies and procurement execution including ancillary supplies, consumables, parts, raw material etc.
    • Collaborate with vendors and contract manufacturing organizations (CMOs) to ensure timely production and delivery of clinical supplies.
    • Act as point of contact for clinical supply packaging, labeling and global depot, courier, broker vendor network.
  1. Clinical Supply Logistics (Storage, Distribution, Reverse Logistics)
    • Ensure appropriate delivery (time, quantity and species) of clinical trial drug and ancillary supply to depots and sites.
    • Monitor inventory levels to prevent shortages or excess stock.
    • Inventory allocation and expiry/shelf-life management to maximize availability while reducing waste.
    • Global storage, import/export, distribution logistics set up and management in support of various restrictions including cold chain, dangerous/hazardous goods, bio-source materials etc.
    • Manage used and unused drug accountability, reverse logistics and destruction at site, depot and study level.
  1. Documentation and Compliance:
    • Maintain accurate documentation of all clinical supply activities, including batch records, shipping records, temperature data etc.
    • Ensure compliance with regulatory requirements (e.g., FDA, EMA) and industry standards (e.g., GMP, GCP) throughout the supply chain process.
    • Participate in audits and inspections, providing support for documentation review and resolution of findings related to clinical supply operations.
  1. Cross-Functional Collaboration:
    • Work closely with Manufacturing/CMC/Tech Ops, Clinical Operations, Regulatory Affairs, Quality Assurance and other relevant departments. Act as point of escalation managing stakeholders’ communications.
    • Communicate effectively with investigational sites and contract research organizations (CROs) to address any supply-related issues and ensure timely resolution.

Qualifications

  • Bachelor's degree in pharmacy, life sciences, supply chain management, or related field.
  • A minimum of 10 years of experience in inventory control, purchasing and procurement, supply chain with at least 2 years of supply chain management experience at a life science company
  • Strong understanding of regulatory requirements and guidelines governing clinical trials (e.g., GMP, GCP).
  • Excellent organizational skills with a keen attention to detail and accuracy.
  • Effective communication and interpersonal skills, with the ability to collaborate across functions and interact with external partners.

What We Can Offer You

This is a unique opportunity to join a team focused on a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology.​ You will have the opportunity to learn new skills and gain a better understanding of the cutting-edge technology. 

We have a comprehensive total compensation package including fully paid medical, dental, and vision benefits for you and your family.   We want all of our employees to have the opportunity to become shareholders and offer new hire stock options.  The Company also offers participation in the annual bonus program.  The salary range for this position is $165,000 - $180,000 annually. We consider various factors when determining the base compensation, including market survey data, experience, qualifications, and geographic location, which means that the actual compensation may vary