About Dermavant:

Dermavant Sciences is a clinical-stage biopharmaceutical company focused on developing innovative therapies for inflammatory skin diseases and medical dermatologic conditions. We are passionate and dedicated to realizing the full potential of biomedical research and to developing and commercializing novel first-in-class or best-in-class therapies that improve patients’ lives. The patient is at the heart of everything we do.

 

Position:

We are seeking exceptional talent for our Nonclinical group. The role of Senior Scientist, Nonclinical will support the preclinical assessment of assets within the Dermavant portfolio at various stages of development. The successful candidate will have a pharmacology/toxicology background as well as a strong understanding of Good Laboratory Practices (GLPs) that will provide broad-based support to align nonclinical efforts with the company’s philosophy of drug development.

 

Responsibilities include:

  • Provide operational support to the Nonclinical group by identifying and liaising with CROs to request bids/proposals to conduct nonclinical studies including pharmacology, non-GLP and GLP safety assessment, and DMPK studies.
  • Manage generation of work orders/POs/invoices for contracted studies; including managing/tracking timelines of studies.
  • Draft, review, and revise, as necessary, CRO nonclinical study protocols/amendments and study reports (non-GLP and GLP) ensuring that they meet regulatory and compliance requirements.
  • Serve as Sponsor Study Monitor overseeing study activities and providing scientific oversight.
  •  Interact/Collaborate closely with other Dermavant functional areas such as Bioanalysis, CMC, and Clinical pharmacology, and project team to design and execute IND-enabling nonclinical studies that aligned with the development plan and program objectives.
  • Effectively communicate and present nonclinical study findings and scientific results to group members, multi-disciplinary research teams, and when, appropriate at external meetings or conferences or preparation of manuscripts for peer-reviewed literature.
  • Contribute to regulatory submissions (INDs, CTAs, IBs, etc) by participating in the authoring, reviewing, and finalization of nonclinical sections of regulatory documents.

 

Qualifications:

  • PhD in a relevant life-science discipline (toxicology or pharmacology preferred) with 2-5 years of pharmaceutical or biotechnology industry experience preferred or Master’s degree with 5-7 years of industry experience.
  • Experience and understanding of Good Laboratory Practices (US FDA 21 CFR Part 58) and working knowledge of FDA, EMA, and ICH guidance documents
  • Experience in designing, monitoring, and interpreting non-GLP and GLP pharmacology, toxicology and DMPK studies
  • Experience in contracting and managing external studies with CROs and academic institutions
  • Ability and commitment to high-quality research and the execution of research plans in a timely and organized manner, with a high level of attention to detail
  • Strong critical thinking and analytical skills
  • Excellent communication, organization, interpersonal and scientific writing skills
  • Proven ability to work independently and to collaborate effectively with a diverse team in a fast-paced and dynamic environment

 

What we look for in our people:

  • Highly motivated self-starter with an entrepreneurial spirit and commitment to personal and career development.
  •  Desire to work in a quickly changing and fast-paced growing business.
  • Unrelenting dedication to delivering results and a desire to shape the strategic goals of the business. Willing to roll up your sleeves to get the job done.
  • Ability to overcome ambiguity and challenge the status quo
  • Manage multiple programs with competing and aggressive timelines, prioritize activities, and work independently.
  • Excellent written and oral communication skills; experienced presenter of key messages to broad audiences including Senior Stakeholders.

 

As an equal opportunity employer, Dermavant is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws.

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