Who We Are

BlackThorn Therapeutics is a computational sciences company that develops proprietary therapeutics focused on neurobehavioral disorders. We have pioneered the development of a computational psychiatry platform to advance our robust pipeline of novel therapeutics. We leverage data-driven approaches to solve the patient selection problem and create treatments that improve patient outcomes.

The Position

We are seeking an individual with drive, candor, and a commitment to learning to join our preclinical team. This individual will report to the Director of Preclinical Sciences but will have significant interactions with members of the biology and chemistry teams.  

Key job functions:

ADME/DMPK Study Operations – This is the primary job function.  Includes: 

• CRO management for ADME/DMPK and toxicology work (>10 CROs)
• Partnering with BlackThorn discovery teams to propose and execute (through a CRO) studies to address programmatic questions
• Reviewing study protocols and review and QC of study reports
• Managing study logistics (e.g. material transfer, timeline expectations, etc.) between BlackThorn and CROs

Data and Document Management – This is a distributed effort between you and a consultant who you will be responsible for: 

• Data upload and data management on our cloud-based system 
• Organizing and maintaining a study protocol database
• Graphing raw in vivo PK data for reporting (Prism and Excel expertise is key)
• Using parsed data from our database to generate SAR plots to support discovery
• Study report writing
• Dissemination of data to stakeholders and project members
• Protocol writing for assays run internally and at our CROs
• Document managing and archiving
  

Project Management – This is a growth opportunity available pending the above work scope is met and includes:

• Drafting and finalizing of monthly project reports with project team leaders and dissemination to company executives
• Preclinical and discovery project timeline, budget, and activity management and reviews
• Preclinical and discovery project risk assessments and management of risk logs

Who You Are

• BS or MS in a pharmaceutically-relevant discipline (chemistry, DMPK, biology)
• 7-10 years of experience working in an industrial pharmaceutical setting, most of that in a technical capacity in a DMPK department
• Highly proficient in Prism Graphpad and Excel data management
• Demonstrated excellent organizational skills and attention to detail
• Proficient in understanding in vitro and in vivo DMPK assay protocols and providing critical feedback
• Highly effective interpersonal and communication skills to work in a collaborative environment with scientists internally, those who are part of our academic partnerships, and those at CROs
• Self-motivated and scientifically-driven individual determined to succeed
• Adaptability to and excitement for working in a fast-paced and rapidly changing start-up environment
  

Preferred

• Experience working on CNS programs and an understanding of the preferred physicochemical properties for crossing the blood brain barrier 

To apply for this position please send your resume/CV which highlights relevant research experience, skills, and qualifications.  We are an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US. 

Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.