Who We Are
BlackThorn Therapeutics is a neurobehavioral health company developing targeted therapeutics, informed by a deep understanding of brain and behavior relationships, to significantly improve patient outcomes. The company has pioneered a proprietary computational psychiatry platform, which leverages bioinformatics, neuroinformatics and artificial intelligence technologies, with the goal of determining a patient's distinct neuroprint to inform the proper on-target treatment option for biologically defined patient subtypes. BlackThorn Therapeutics has completed a Phase 1 trial of BTRX-335140, a selective kappa opioid receptor antagonist, and is conducting IND-enabling studies for BTRX-323511, a selective vasopressin 1a receptor antagonist. The company also has a drug discovery program directed at novel therapeutic targets for neurobehavioral disorders.
The Position
The Principal Research Scientist is responsible for providing neuroscience, analytics and machine learning expertise through the implementation of BlackThorn’s computational psychiatry platform in innovative ways to meet BlackThorn’s present and future needs.
- Under the guidance and direction of the Chief Architect, work on machine learning initiatives and scientific aspects associated with the platform, including: (1) research analysis, (2) data analysis and reports, (3) data architectures, (4) interpret and synthesize results, (5) advanced analytics, and (6) innovation
- Work closely with BlackThorn’s data science and clinical teams to develop innovative solutions to support BlackThorn’s computational psychiatry platform efforts
- Provide input to technology teams and data engineering teams on capabilities needed
- Work closely with BlackThorn’s clinical team to develop and launch compliant data solutions
- Increase visibility of BlackThorn’s computational psychiatry platform through paper publications, presentations, and presence across relevant neuroscience research communities
Who You Are
At BlackThorn Therapeutics, we are looking for a highly motivated individual with passion for implementing data-driven approaches to solve complex business problems.
Qualifications and Education Requirements:
- Degree in computer science, machine learning, statistics, computational neuroscience, physics, or related field
- Experience in computational neuroscience is preferred
- Solid understanding of statistics, data analytics, machine learning, and deep learning algorithms and techniques is required
- Hands-on experience with CNNs, RNNs, and LSTMs is preferred
- Experience in biotech/pharma and clinical trials is a plus
- Hands-on experience with deep learning frameworks such as Tensorflow, Theano, Caffe, and/or Torch is required
- Hands-on experience with Hive, Apache Hadoop, Spark, Java/Python is required
- Scientific thinking and the ability to invent, a track record of thought leadership and contributions that have advanced the field
- Experience working with Big Data, Cloud, AI or Machine Learning technologies
- Strong understanding of machine learning, cognitive computing, natural language processing, statistics, and modeling techniques
- Ability to work with senior client executives
- Experience working in complex data projects
- Experience designing and developing data cleansing routines utilizing typical data quality functions involving standardization, transformation, rationalization, linking and matching
- Experience working with multi-Terabyte data sets
- Development experience coding in Java and/or Python
- Keen problem solver with strong motivation to impact positive results
- Experience working with standard Linux tools, with emphasis on scripting and automation
- Non-essential but welcome additional skills and experience: AWS, GCP or MS Azure
- Strong communication skills and the ability to work with others in a closely collaborative team environment