Director of Clinical Operations



This role is based at the Iambic San Diego headquarters. The Director of Clinical Operations will be responsible for overseeing and directing all aspects of clinical operations within the organization. This leadership role requires strategic planning, effective management, and collaboration with cross-functional teams to ensure the successful execution of clinical trials and studies.



  • Develop and implement strategic plans for clinical operations to support organizational goals and objectives.
  • Manage clinical trial budgets, resources, and timelines to ensure efficient and cost-effective execution.
  • Oversee selection and management of clinical research sites, vendors and partners.
  • Ensure compliance with regulatory requirements, good clinical practice and internal SOPs.
  • Build an efficient Clinical Operations group over time to support new studies and advancement of pipeline assets.
  • Collaborate with other functional areas such as clinical research, regulatory affairs, data management, and project management to support the clinical development process.
  • Monitor and analyze KPIs to assess progress and quality of clinical trials.
  • Identify and mitigate risks and issues that may impact the successful conduct of clinical studies.
  • Serve as a key point of contact for internal stakeholders, external partners and regulatory agencies.



  • Bachelor’s degree in related discipline.
  • 10+ years experience in Clinical Operations.
  • Experience overseeing biotech phase 1 clinical trials; experience with oncology programs is preferred.
  • Prior experience managing direct reports within a clinical research organization or CRO



Iambic is disrupting the therapeutics landscape with its cutting-edge generative AI drug discovery platform. We have assembled a world-class team that unites pioneering AI experts and seasoned drug hunters with strong track records of success in delivering clinically validated breakthrough treatments.The Iambic platform has been demonstrated to deliver high quality, differentiated drugs to clinic with unprecedented speed and across multiple target classes and mechanisms of action.  We are focused on the advancement of our internal pipeline of clinical assets to address urgent unmet patient need in oncology and other therapeutic areas.




The culture and mission at Iambic Therapeutics are profoundly influenced and strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.



We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life Insurance, 401K matching, and unlimited vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.


Salary Range from $153,000-$260,000 per year


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