Lead Product Formulator
Full Time
Overview:
Lead the research, formulation, refinement and testing of complex product formulations for a leading nutraceutical company.
Primary Responsibilities:
- Research current products with related goals and all of the ingredients used. Research pharmaceutical medicines and other synthetic chemicals with known related effects; understand the mechanisms through which they operate.
- Create and maintain a chemical database of all the possible ingredients that could be used in any of our formulations, with all the relevant info on each (active compounds, primary and secondary mechanisms of action, contraindications, dose ranges, safety data, molecular structure, links to research, etc.)
- Develop product hypothesis for new products that include the mechanisms and pathways we are seeking to target, and proposed ingredients that might appropriately affect those pathways, supported by good research. Work with our medical and scientific advisors to develop the hypothesis and testing process.
- Conduct full literature review on all ingredients, factoring safety, efficacy, interactions, delivery needs, half life, etc.
- Research the difference between various forms of the same nutrient, plants with similar mechanisms of action, active ingredient extraction and standardization processes, etc. Research and decide on ingredient sourcing.
- Research and decide on necessary inactive ingredients for tableting, manufacturing, etc., aligned with the company’s philosophy and quality control standards.
- Search for nutraceuticals that have similar mechanisms of action to pharmaceuticals/research chemicals.
- Generate hypothesis regarding ingredient interactions and synergies, and processes to test the hypotheses.
- Conduct internal trials to refine formulations.
- Collaborate with the Medical Director, the head of Product Development, and CRO’s to create and run clinical trials.
- Create and maintain safety data sheets for each product. Create and maintain relevant medical disclaimers and product labels.
- Work with marketing and legal team to develop research supported claims for each product. Work with the content team to develop information and FAQs on each product.
- Coordinate manufacturing team to create ingredient testing and product manufacturing protocols to meet our quality control standards.
- Engage external resources as needed for food and flavor sciences, ingredient testing, stability/ shelf life testing, etc.
- Reformulate factoring regulatory differences for different countries or change in regulations.
- Research and experiment with improving delivery mechanisms for ingredients.
- Assist creation of quantified self app to support our community in their own personalized optimization, and to provide us relevant bioinformatics
- Curate non-ingestible neurotechnology based on literature review
Product Landscape:
Supplements
Branded products in the Qualia line. Direct to consumer products related to psycho-neuro wellbeing: sleep, calmness, pain, focus, etc.
Branded products in a general wellbeing line: microbiomics, inflammation, life extension, cell health, etc.
B2C formulation for other companies.
Branded line of products for integrative doctors for more specific therapeutic use.
Developing different delivery mechanisms for product
Personalized formulations based on biodata
Product Development Approach:
Only creating products that are category defining.
Complex formulations: addressing complete physiological pathways and interactions across multiple pathways. Working to support endogenous regulation rather than override it. Designing for positive synergies.
Immediate and long term benefit. Safety and efficacy.
Highest quality ingredients, factoring form, purity and delivery.
Working towards optimal nutrient delivery.
Research supported approach. Scientific integrity.
Stay at the cutting edge of the fields. Versioning with meaningful new developments.
Every part of product development matters: sourcing, inactive ingredients, manufacturing process, level of research, claims, storage, etc.
Success Criteria:
Develop new products and versions that meet safety, efficacy, uniqueness and customer satisfaction objectives.
Meet agreed-upon timelines and annual objectives for number of new product launches.
Ensure product quality control standards.
Qualifications:
Experience formulating complex, high-end nutraceuticals.
Experience working with clinical trials.
Knowledge of current GMP guidelines.
Knowledge of dietary ingredient regulation.
Ability to interpret preferred methods of ingredient testing (HPLC, MS, etc.)and certificates of analysis, etc.
Graduate degree in related fields of science or equivalent relevant study.
Passion for these topics and this type of work.
Ideal:
Background in nutritional science, nutrigenomics, neurochemistry/ psychoneuropharmacology, herbalism, microbiomics, and integrative medicine.
Formulation experience for high end supplement companies.
Knowledge and deep interest in nootropics and cognitive chemistry.
Understanding of food science and capable of addressing organoleptic concerns.
Familiarity with advanced delivery systems.
Skills:
Ability to communicate and effectively collaborate with scientists and nonscientists.
Prior experience in formulating products for various foreign markets like EU, Japan, Australia, Canada, etc., preferred.
Ability to comprehend technical scientific publications and to conduct meta analysis/ structured review of the literature.
Ability to engage contributors and synthesize input from many sources.
Technical writing skills
Opportunity:
Develop category defining products that meaningfully improve quality of life
Play a central role in an organization aspiring to help shape human wellbeing globally
Work with an exceptional and dedicated team towards that mission.
Belong to a culture committed to practicing its philosophy of personal optimization.
Please apply through TriNet Link
A cover letter is appreciated. A few worthwhile items to include are:
Why you are interested in working at Neurohacker Collective?
Why it seems like a good fit
What your dream work is
Any other info you’d like to share :)